The study of all epigenetic alterations in an organism, including modifications to its DNA and histones, is known as epigenomics. High throughput DNA sequencing is paired with whole genome sequencing and sodium bisulfite conversion of the sequence. Whereas unmethylated cytosines are transformed into uracil, methylcytosines are shielded from conversion by the sodium bisulfite reaction...

- Methylation Sequencing
- Whole Genome Bisulfite Sequencing
- Targeted Bisulfite Sequencing
- Chromatin Immunoprecipitation (ChIP) Sequencing Service
- 5mC/5hmC Sequencing

Methylation Sequencing

DNA methylation is measured by a procedure called methylation sequencing, which involves a precision-targeted approach used to quantitatively measure the levels of DNA methylation at specific CpG sites.

Whole Genome Bisulfite Sequencing

Comprehensive knowledge of DNA methylation patterns over the entire genome is provided by whole genome bisulfite sequencing, which enables the analysis of both methylated and unmethylated cytosines..

Targeted Bisulfite Sequencing

This technique is frequently used to verify the regions found in genome-wide methylation analyses, such as methylated DNA immunoprecipitation sequencing, whole-genome bisulfite sequencing, and reduced representation bisulfite sequencing, as well as to test hypotheses about the target regions of interest.

Chromatin Immunoprecipitation (ChIP) Sequencing Service

ChIP-sequencing (ChIP-Seq) is a technique that identifies genome-wide DNA binding sites for transcription factors and other proteins by combining sequencing with ChIP experiments. It is a useful tool for researching the interactions between proteins and DNA.

5mC/5hmC Sequencing

5mC/5hmC sequencing service makes use of several reliable, well-established systems that are very accurate, simple to use, and efficient. 5mC may be detected with High Performance Liquid Chromatography..

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