Screening Compounds

Small molecules are organic compounds with low molecular weight that can easily diffuse across cell membranes and modulate biological processes — often by binding to proteins, nucleic acids, or receptors..

Natural products are chemical compounds produced by plants, microorganisms, marine organisms, and animals. They have historically been the richest source of drug leads, and many modern medicines are natural products or semisynthetic derivatives..

- Alkaloids (Nitrogen-containing)

- Terpenoids (Isoprenoids)

- Polyketides

- Phenolics & Flavonoids

- Glycosides

Peptides and peptidomimetics are vital classes of molecules in modern drug discovery, especially for targets considered “undruggable” by small molecules (e.g., protein–protein interactions)..

Nucleic acid–based molecules are therapeutics and research tools derived from DNA or RNA that modulate gene expression at the genetic or post-transcriptional level. They represent a major pillar of precision medicine, especially for cancer, genetic disorders, and viral diseases..

Biologics are therapeutic products derived from living systems (cells, microorganisms, or biological processes). They represent the fastest-growing segment of the pharmaceutical industry and are central to modern treatment of cancer, autoimmune diseases, infectious diseases, and rare genetic disorders..

Covalent binders are small molecules or biologics that form a covalent (irreversible or reversible) bond with their biological target, usually an amino-acid side chain in a protein. Once controversial, they are now a mainstream drug-discovery strategy, especially in oncology and immunology..