In Vitro Cytotoxicity Analysis

A cytotoxicity assay is a laboratory test used to determine toxicity in drug, pharmaceutical product, cosmetics and medical devices. These assays are widely used in drug development, cancer research, and toxicology to evaluate the effects of treatments or compounds on cell viability.

Services:

» MTT Assay
» LDH Assay (Lactate Dehydrogenase Release)
» Trypan Blue Exclusion Assay
» Resazurin (Alamar Blue) Assay
» Annexin V/Propidium Iodide (PI) Staining
» Caspase Activity Assays

The biocompatibility and toxicity of materials for application in pharmaceuticals, medical devices, and related goods are currently assessed using mammalian tissue culture methods.

Various cytotoxicity tests are available to characterize the toxicity of medical device components or materials and  products.

- MEM Elution Assay
- Agar Overlay Cytotoxicity Assay
- Agar Diffusion Test
- XTT / MTT Staining
- Neutral Red Uptake (NRU) Staining

These services provide essential support for research, drug discovery, toxicity testing, and various other biomedical applications. Outsourcing these services allows organizations to access specialized technical expertise, state-of-the-art facilities, and standardized protocols.

Assay Formats Used

- Flow cytometry-based assays (e.g., Annexin V/PI staining)
- LDH release assays
- Fluorescent assays (e.g., Alamar Blue)
- Microscopic observation

Example Results

What a Cytotoxicity Assay Result Looks Like

Note: A representative cell-viability dose-response curve used to calculate IC50/CC50. Your specific compound's curve and calculated values are included in your final report. The chart above is illustrative artwork for orientation only and does not represent actual client data.